-Mike
Certified Mad Doctor and HoP High Priest of Nutella
A buckuht n a hooze! -Valura
quote:You're kidding, right? This stuff is awesome! My Masters degree is in molecular biology and molecular genetics, so I did a bit of molecular evolution work (although I worked with viruses, not dogs). This sort of thing is so cool! I don't know who first thought up the DTm technique for estimating sequence identity, but it's elegant and ingenious. I've never actually used it myself, though. The issue of dog evolution is an interesting one because humans have actively intervened in the process generating different breeds, so it's a fascinating study into non-random evolution. But I've bookmarked this link for reading at a future time when I'm not studying for boards. Wow.
The degree to which two single-copy DNA sequences have diverged can be estimated by the DTm which is the difference between the melting temperature (the point where 50% of DNA is double stranded) for a homologous duplex (i.e. both strands from the same species) and a heterologous duplex (with constituent strands from different species). the value is normalized for the final percentage of hybridization and designated DTmR (Ref. 4).
-Mike
Certified Mad Doctor and HoP High Priest of Nutella
A buckuht n a hooze! -Valura
quote:I never knew Glass was a composer!
The latest specimens to reach your local CD shop are Glass's ambitious Symphony No. 5 and John Adams's exuberant "Century Rolls."
quote:clever git.
Glass explores religion
While the whimsical aspects of the "Century Rolls" pieces suggest that Adams is on vacation from the seriousness of large-scale works like "The Death of Klinghoffer" and the great "Nixon in China," the same can't be said of Glass, whose compositions explore moral, philosophical, and religious issues as well as purely aesthetic dimensions.
His massive Symphony No. 5 is no exception. Conceived as a celebration of the millennium at the Salzburg Festival in Germany, it combines Glass's typically pulsing rhythms with a text that brings together quotations from what Glass considers the world's great "wisdom" traditions, sung by vocal soloists, a children's choir, and a full chorus. Its words are taken from the Bible, the Koran, a Creation story of the Zuni Indians, the Popul Vuh scriptures of the ancient Mayans, and the Bhagavad-Gita of Hinduism, among other sources. They are all translated into English, not because Glass avoids multicultural diversity - he once composed a whole opera in Sanskrit - but because he wants to emphasize their common insights rather than their different perspectives.
A feast for the mind and heart
Your life is ending one minute at a time...
So live it.
Why?
POI THEO(R)IST
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